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The 16 sign combinations in 78830573871633653580 +/- 21 +/-
9 +/- 6 +/- 5 produce 16 distinct consecutive primes in an
interval of 83 numbers. This is the first occurrence of the
smallest possible interval with 16 distinct primes in the
pattern n +/- a +/- b +/- c +/- d. [Andersen]
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