This number is a prime.
The first edition of The Music of Primes by Marcus du Sautoy was published in 2003. [Post]
During a quarter century career as a professional stuntman from 1968 to 1993, Dick Sheppard of Gloucester, England, wrecked a total of 2003 automobiles. [Dobb]
Lance Armstrong, in 2003 (at the age of 31), became the 2nd person ever to win the Tour De France 5 times consecutively, beating the runner-up Jan Ullrich by 61 seconds. Note that 2, 5, 31, 61 and 2003 are all prime numbers. [Hartley]
The first year of the 21st century is not only prime, but has a prime concatenation of all years from 2000 through itself. I.e., 2000200120022003 is prime. [Post]
The only known prime of the form 2*10^p+p, where p and p+4 are primes. [Firoozbakht]
2003 is formed from the first two primes (2 and 3) separated by two 0's. You can get the next two primes by adding 23, then 2*3. [Merickel]